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Nxf3: a middleman with the right connections for unspliced piRNA precursor export

RNA export is tightly coupled to splicing in metazoans. In the Drosophila germline, precursors for the majority of Piwi-interacting RNAs (piRNAs) are unspliced. In this issue of Genes & Development, Kneuss and colleagues (pp. 1208–1220) identify Nxf3 as a novel germline-specific export adapter f...

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Detalles Bibliográficos
Autores principales: Mendel, Mateusz, Pillai, Ramesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719615/
https://www.ncbi.nlm.nih.gov/pubmed/31481534
http://dx.doi.org/10.1101/gad.330530.119