MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer

Tumors display increased uptake and processing of nutrients to fulfill the demands of rapidly proliferating cancer cells. Seminal studies have shown that the proto-oncogene MYC promotes metabolic reprogramming by altering glutamine uptake and metabolism in cancer cells. How MYC regulates the metabol...

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Detalles Bibliográficos
Autores principales: Venkateswaran, Niranjan, Lafita-Navarro, M. Carmen, Hao, Yi-Heng, Kilgore, Jessica A., Perez-Castro, Lizbeth, Braverman, Jonathan, Borenstein-Auerbach, Nofit, Kim, Min, Lesner, Nicholas P., Mishra, Prashant, Brabletz, Thomas, Shay, Jerry W., DeBerardinis, Ralph J., Williams, Noelle S., Yilmaz, Omer H., Conacci-Sorrell, Maralice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719621/
https://www.ncbi.nlm.nih.gov/pubmed/31416966
http://dx.doi.org/10.1101/gad.327056.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719621/
https://www.ncbi.nlm.nih.gov/pubmed/31416966
http://dx.doi.org/10.1101/gad.327056.119

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