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Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination

The vast majority of eukaryotes possess two DNA recombinases: Rad51, which is ubiquitously expressed, and Dmc1, which is meiosis-specific. The evolutionary origins of this two-recombinase system remain poorly understood. Interestingly, Dmc1 can stabilize mismatch-containing base triplets, whereas Ra...

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Detalles Bibliográficos
Autores principales: Steinfeld, Justin B., Beláň, Ondrej, Kwon, Youngho, Terakawa, Tsuyoshi, Al-Zain, Amr, Smith, Michael J., Crickard, J. Brooks, Qi, Zhi, Zhao, Weixing, Rothstein, Rodney, Symington, Lorraine S., Sung, Patrick, Boulton, Simon J., Greene, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719624/
https://www.ncbi.nlm.nih.gov/pubmed/31371435
http://dx.doi.org/10.1101/gad.328062.119