Cargando…

Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination

The vast majority of eukaryotes possess two DNA recombinases: Rad51, which is ubiquitously expressed, and Dmc1, which is meiosis-specific. The evolutionary origins of this two-recombinase system remain poorly understood. Interestingly, Dmc1 can stabilize mismatch-containing base triplets, whereas Ra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Steinfeld, Justin B., Beláň, Ondrej, Kwon, Youngho, Terakawa, Tsuyoshi, Al-Zain, Amr, Smith, Michael J., Crickard, J. Brooks, Qi, Zhi, Zhao, Weixing, Rothstein, Rodney, Symington, Lorraine S., Sung, Patrick, Boulton, Simon J., Greene, Eric C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719624/ https://www.ncbi.nlm.nih.gov/pubmed/31371435 http://dx.doi.org/10.1101/gad.328062.119

Ejemplares similares

Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function
por: Špírek, Mário, et al.
Publicado: (2021)

Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments
por: Meir, Aviv, et al.
Publicado: (2022)

Structure and function of the RAD51B-RAD51C-RAD51D-XRCC2 tumour suppressor
por: Greenhough, Luke A., et al.
Publicado: (2023)

DMC1 attenuates RAD51-mediated recombination in Arabidopsis
por: Da Ines, Olivier, et al.
Publicado: (2022)

The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments
por: Crickard, J Brooks, et al.
Publicado: (2019)

A comparative analysis of Dmc1 and Rad51 nucleoprotein filaments
por: Sheridan, Sean D., et al.
Publicado: (2008)

Mechanisms of distinctive mismatch tolerance between Rad51 and Dmc1 in homologous recombination
por: Xu, Jingfei, et al.
Publicado: (2021)

Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homologous DNA repair and XX ovarian dysgenesis
por: Zhao, Weixing, et al.
Publicado: (2015)

HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51
por: Anand, Roopesh, et al.
Publicado: (2021)

On the role of AtDMC1, AtRAD51 and its paralogs during Arabidopsis meiosis
por: Pradillo, Mónica, et al.
Publicado: (2014)

Meiotic Recombination in Arabidopsis Is Catalysed by DMC1, with RAD51 Playing a Supporting Role
por: Da Ines, Olivier, et al.
Publicado: (2013)

Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament
por: Ma, Chu Jian, et al.
Publicado: (2017)

Stimulation of fission yeast and mouse Hop2-Mnd1 of the Dmc1 and Rad51 recombinases
por: Ploquin, Mickaël, et al.
Publicado: (2007)

Differing Requirements for RAD51 and DMC1 in Meiotic Pairing of Centromeres and Chromosome Arms in Arabidopsis thaliana
por: Da Ines, Olivier, et al.
Publicado: (2012)

The RAD51 and DMC1 homoeologous genes of bread wheat: cloning, molecular characterization and expression analysis
por: Devisetty, Upendra Kumar, et al.
Publicado: (2010)

Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing
por: Kobayashi, Wataru, et al.
Publicado: (2016)

The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates
por: Hinch, Anjali Gupta, et al.
Publicado: (2020)

A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling
por: Taylor, Martin R.G., et al.
Publicado: (2016)

Rad51 and Dmc1 Form Mixed Complexes Associated with Mouse Meiotic Chromosome Cores and Synaptonemal Complexes
por: Tarsounas, Madalena, et al.
Publicado: (1999)

Identification of fidelity-governing factors in human recombinases DMC1 and RAD51 from cryo-EM structures
por: Luo, Shih-Chi, et al.
Publicado: (2021)

Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins
por: Belan, Ondrej, et al.
Publicado: (2021)

Rad51 gain-of-function mutants that exhibit high affinity DNA binding cause DNA damage sensitivity in the absence of Srs2
por: Malik, Punjab S., et al.
Publicado: (2008)

Meiotic Crossover Control by Concerted Action of Rad51-Dmc1 in Homolog Template Bias and Robust Homeostatic Regulation
por: Lao, Jessica P., et al.
Publicado: (2013)

The FLIP-FIGNL1 complex regulates the dissociation of RAD51/DMC1 in homologous recombination and replication fork restart
por: Zhang, Qianting, et al.
Publicado: (2023)

Small Rad51 and Dmc1 Complexes Often Co-occupy Both Ends of a Meiotic DNA Double Strand Break
por: Brown, M. Scott, et al.
Publicado: (2015)

RAD51AP1 mediates RAD51 activity through nucleosome interaction
por: Pires, Elena, et al.
Publicado: (2021)

The Recombinases Rad51 and Dmc1 Play Distinct Roles in DNA Break Repair and Recombination Partner Choice in the Meiosis of Tetrahymena
por: Howard-Till, Rachel A., et al.
Publicado: (2011)

Down-Regulation of Rad51 Activity during Meiosis in Yeast Prevents Competition with Dmc1 for Repair of Double-Strand Breaks
por: Liu, Yan, et al.
Publicado: (2014)

Super-resolution imaging of RAD51 and DMC1 in DNA repair foci reveals dynamic distribution patterns in meiotic prophase
por: Slotman, Johan A., et al.
Publicado: (2020)

FIGNL1 AAA+ ATPase remodels RAD51 and DMC1 filaments in pre-meiotic DNA replication and meiotic recombination
por: Ito, Masaru, et al.
Publicado: (2023)

Single-molecule visualization of human RECQ5 interactions with single-stranded DNA recombination intermediates
por: Xue, Chaoyou, et al.
Publicado: (2020)

Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination
por: Taylor, Martin R.G., et al.
Publicado: (2015)

A mutant form of Dmc1 that bypasses the requirement for accessory protein Mei5-Sae3 reveals independent activities of Mei5-Sae3 and Rad51 in Dmc1 filament stability
por: Reitz, Diedre, et al.
Publicado: (2019)

Rdh54 stabilizes Rad51 at displacement loop intermediates to regulate genetic exchange between chromosomes
por: Keymakh, Margaret, et al.
Publicado: (2022)

RAD51AP1 and RAD54L Can Underpin Two Distinct RAD51-Dependent Routes of DNA Damage Repair via Homologous Recombination
por: Selemenakis, Platon, et al.
Publicado: (2022)

Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination
por: Lorenz, Alexander, et al.
Publicado: (2014)

Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state
por: Špírek, Mário, et al.
Publicado: (2018)

Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption
por: Colavito, Sierra, et al.
Publicado: (2009)

Mechanisms and Regulation of Mitotic Recombination in Saccharomyces cerevisiae
por: Symington, Lorraine S., et al.
Publicado: (2014)

Roles of XRCC2, RAD51B and RAD51D in RAD51-Independent SSA Recombination
por: Serra, Heïdi, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_triir39s6nns6aqodj3slnocgq