The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1

TRIM71/LIN-41, a phylogenetically conserved regulator of development, controls stem cell fates. Mammalian TRIM71 exhibits both RNA-binding and protein ubiquitylation activities, but the functional contribution of either activity and relevant primary targets remain poorly understood. Here, we demonst...

Descripción completa

Detalles Bibliográficos
Autores principales: Welte, Thomas, Tuck, Alex C., Papasaikas, Panagiotis, Carl, Sarah H., Flemr, Matyas, Knuckles, Philip, Rankova, Aneliya, Bühler, Marc, Großhans, Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719626/
https://www.ncbi.nlm.nih.gov/pubmed/31371437
http://dx.doi.org/10.1101/gad.328492.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719626/
https://www.ncbi.nlm.nih.gov/pubmed/31371437
http://dx.doi.org/10.1101/gad.328492.119

Ejemplares similares