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Calcium-ligand variants of the myocilin olfactomedin propeller selected from invertebrate phyla reveal cross-talk with N-terminal blade and surface helices

Olfactomedins are a family of modular proteins found in multicellular organisms that all contain five-bladed β-propeller olfactomedin (OLF) domains. In support of differential functions for the OLF propeller, the available crystal structures reveal that only some OLF domains harbor an internal calci...

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Detalles Bibliográficos
Autores principales: Hill, Shannon E., Cho, Hayeon, Raut, Priyam, Lieberman, Raquel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719662/
https://www.ncbi.nlm.nih.gov/pubmed/31478904
http://dx.doi.org/10.1107/S205979831901074X