IL-4 Augments IL-31/IL-31 Receptor Alpha Interaction Leading to Enhanced Ccl 17 and Ccl 22 Production in Dendritic Cells: Implications for Atopic Dermatitis

Severe pruritus is a characteristic feature of atopic dermatitis (AD) and is closely related to its activity. Recent studies have shown that IL-31 is a key determinant of pruritus in AD. Anti-IL-31 receptor alpha (IL-31RA) antibody treatment has also been reported to improve pruritus clinically, sub...

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Detalles Bibliográficos
Autores principales: Miake, Sho, Tsuji, Gaku, Takemura, Masaki, Hashimoto-Hachiya, Akiko, Vu, Yen Hai, Furue, Masutaka, Nakahara, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719908/
https://www.ncbi.nlm.nih.gov/pubmed/31434203
http://dx.doi.org/10.3390/ijms20164053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719908/
https://www.ncbi.nlm.nih.gov/pubmed/31434203
http://dx.doi.org/10.3390/ijms20164053

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