A Brønsted Acid-Catalyzed Multicomponent Reaction for the Synthesis of Highly Functionalized γ-Lactam Derivatives

Brønsted acids catalyze a multicomponent reaction of benzaldehyde with amines and diethyl acetylenedicarboxylate to afford highly functionalized γ-lactam derivatives. The reaction consists of a Mannich reaction of an enamine to an imine, both generated in situ, promoted by a phosphoric acid catalyst...

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Detalles Bibliográficos
Autores principales: del Corte, Xabier, Martinez de Marigorta, Edorta, Palacios, Francisco, Vicario, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719937/
https://www.ncbi.nlm.nih.gov/pubmed/31416281
http://dx.doi.org/10.3390/molecules24162951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719937/
https://www.ncbi.nlm.nih.gov/pubmed/31416281
http://dx.doi.org/10.3390/molecules24162951

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