Modulation of Apoptotic Cell Death and Neuroprotective Effects of Glutathione—L-Dopa Codrug Against H(2)O(2)-Induced Cellular Toxicity

The L-3,4-dihydroxyphenylalanine (LD) is the gold standard drug currently used to manage Parkinson’s disease (PD) and to control its symptoms. However, LD could cause disease neurotoxicity due to the generation of pro-oxidant intermediates deriving from its autoxidation. In order to overcome this li...

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Detalles Bibliográficos
Autores principales: Franceschelli, Sara, Lanuti, Paola, Ferrone, Alessio, Gatta, Daniela Maria Pia, Speranza, Lorenza, Pesce, Mirko, Grilli, Alfredo, Cacciatore, Ivana, Ricciotti, Emanuela, Di Stefano, Antonio, Miscia, Sebastiano, Felaco, Mario, Patruno, Antonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720001/
https://www.ncbi.nlm.nih.gov/pubmed/31430883
http://dx.doi.org/10.3390/antiox8080319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720001/
https://www.ncbi.nlm.nih.gov/pubmed/31430883
http://dx.doi.org/10.3390/antiox8080319

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