A Ploidy Increase Promotes Sensitivity of Glioma Stem Cells to Aurora Kinases Inhibition

Glioma stem cells account for glioblastoma relapse and resistance to conventional therapies, and protein kinases, involved in the regulation of the mitotic machinery (i.e., Aurora kinases), have recently emerged as attractive therapeutic targets. In this study, we investigated the effect of Aurora k...

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Detalles Bibliográficos
Autores principales: Cilibrasi, Chiara, Guzzi, Andrèe, Bazzoni, Riccardo, Riva, Gabriele, Cadamuro, Massimiliano, Hochegger, Helfrid, Bentivegna, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720056/
https://www.ncbi.nlm.nih.gov/pubmed/31531022
http://dx.doi.org/10.1155/2019/9014045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720056/
https://www.ncbi.nlm.nih.gov/pubmed/31531022
http://dx.doi.org/10.1155/2019/9014045

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