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Spatio-temporal characterization of S- and M/L-cone degeneration in the Rd1 mouse model of retinitis pigmentosa

BACKGROUND: The Pde6brd1 (Rd1) mouse is widely used as a murine model for human retinitis pigmentosa. Understanding the spatio-temporal patterns of cone degeneration is important for evaluating potential treatments. In the present study we performed a systematic characterization of the spatio-tempor...

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Detalles Bibliográficos
Autores principales: Narayan, Daniel S., Ao, Jack, Wood, John P. M., Casson, Robert J., Chidlow, Glyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720080/
https://www.ncbi.nlm.nih.gov/pubmed/31481030
http://dx.doi.org/10.1186/s12868-019-0528-2