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An essential role of RNF187 in Notch1 mediated metastasis of hepatocellular carcinoma

BACKGROUND: Aberrant activation of Notch signaling has been causally linked to the metastasis of hepatocellular carcinoma (HCC), however the underlying molecular mechanisms are still poorly understood. RING finger protein 187 (RNF187) was recently revealed to be a driver of several cancers, but its...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Chen, Jiewei, Yong, Juanjuan, Qiao, Liang, Xu, Leibo, Liu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720101/
https://www.ncbi.nlm.nih.gov/pubmed/31477177
http://dx.doi.org/10.1186/s13046-019-1382-x