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Carcinogenic effect of potassium octatitanate (POT) fibers in the lung and pleura of male Fischer 344 rats after intrapulmonary administration

BACKGROUND: Potassium octatitanate fibers (K(2)O•8TiO(2), POT fibers) are used as an asbestos substitute. Their physical characteristics suggest that respirable POT fibers are likely to be carcinogenic in the lung and pleura. However, previous 2-year inhalation studies reported that respired POT fib...

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Detalles Bibliográficos
Autores principales: Abdelgied, Mohamed, El-Gazzar, Ahmed M., Alexander, William T., Numano, Takamasa, Iigou, Masaaki, Naiki-Ito, Aya, Takase, Hiroshi, Hirose, Akihiko, Taquahashi, Yuhji, Kanno, Jun, Abdelhamid, Mona, Abdou, Khaled Abbas, Takahashi, Satoru, Alexander, David B., Tsuda, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720102/
https://www.ncbi.nlm.nih.gov/pubmed/31477126
http://dx.doi.org/10.1186/s12989-019-0316-2