Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation

Ubiquitin (Ub) is a small protein that post-translationally modifies a variety of substrates in eukaryotic cells to modulate substrate function. The ability of Ub to interact with numerous protein domains makes Ub an attractive scaffold for engineering ubiquitin variants (UbVs) with high target spec...

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Detalles Bibliográficos
Autores principales: Gabrielsen, Mads, Buetow, Lori, Kowalczyk, Dominika, Zhang, Wei, Sidhu, Sachdev S., Huang, Danny T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720194/
https://www.ncbi.nlm.nih.gov/pubmed/31303481
http://dx.doi.org/10.1016/j.str.2019.06.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720194/
https://www.ncbi.nlm.nih.gov/pubmed/31303481
http://dx.doi.org/10.1016/j.str.2019.06.008

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