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Identification and Characterization of Mutations in Ubiquitin Required for Non-covalent Dimer Formation
Ubiquitin (Ub) is a small protein that post-translationally modifies a variety of substrates in eukaryotic cells to modulate substrate function. The ability of Ub to interact with numerous protein domains makes Ub an attractive scaffold for engineering ubiquitin variants (UbVs) with high target spec...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720194/ https://www.ncbi.nlm.nih.gov/pubmed/31303481 http://dx.doi.org/10.1016/j.str.2019.06.008 |