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Comparison of the TLR4/NFκB and NLRP3 signalling pathways in major organs of the mouse after intravenous injection of lipopolysaccharide

Context: Lipopolysaccharide (LPS) is often used to induce immunoinflammatory reactions. TLR4/NFκB and NLRP3 signalling are major factors for inflammation. Dexamethasone (DXM) has an anti-immunoinflammatory effect. Objective: To investigate the inflammatory reaction in pathological changes of organs...

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Detalles Bibliográficos
Autores principales: Gong, Qin, He, Luling, Wang, Mulan, Zuo, Shasha, Gao, Hongwei, Feng, Yulin, Du, Lijun, Luo, Yingying, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720225/
https://www.ncbi.nlm.nih.gov/pubmed/31446815
http://dx.doi.org/10.1080/13880209.2019.1653326