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Reduced expression of the Ion channel CFTR contributes to airspace enlargement as a consequence of aging and in response to cigarette smoke in mice

Chronic Obstructive Pulmonary Disease (COPD) is a complex disease resulting in respiratory failure and represents the third leading cause of global death. The two classical phenotypes of COPD are chronic bronchitis and emphysema. Owing to similarities between chronic bronchitis and the autosomal-rec...

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Detalles Bibliográficos
Autores principales: Wellmerling, Jack H., Chang, Sheng-Wei, Kim, Eunsoo, Osman, Wissam H., Boyaka, Prosper N., Borchers, Michael T., Cormet-Boyaka, Estelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720379/
https://www.ncbi.nlm.nih.gov/pubmed/31477092
http://dx.doi.org/10.1186/s12931-019-1170-3