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An inherent T cell deficit in healthy males to C. neoformans infection may begin to explain the sex susceptibility in incidence of cryptococcosis

BACKGROUND: Cryptococcus neoformans, the causative agent of cryptococcosis, causes ~ 181,000 deaths annually, with males having a higher incidence of disease than females (7M:3F). The reason for this sex bias remains unclear. We hypothesized that this disparity was due to biological differences betw...

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Detalles Bibliográficos
Autores principales: Guess, Tiffany E., Rosen, Joseph, Castro-Lopez, Natalia, Wormley, Floyd L., McClelland, Erin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720413/
https://www.ncbi.nlm.nih.gov/pubmed/31477151
http://dx.doi.org/10.1186/s13293-019-0258-2