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Dually Acting Nonclassical 1,4-Dihydropyridines Promote the Anti-Tuberculosis (Tb) Activities of Clofazimine

The number of effective antituberculotic drugs is strongly limited to four first-line drugs in standard therapy. In case of resistances second-line antibiotics are used with a poor efficacy and tolerability. Therefore, novel antituberculotic drugs are urgently needed. We synthesized novel nonclassic...

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Detalles Bibliográficos
Autores principales: Lentz, Fabian, Reiling, Norbert, Spengler, Gabriella, Kincses, Annamária, Csonka, Andrea, Molnár, Joseph, Hilgeroth, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720424/
https://www.ncbi.nlm.nih.gov/pubmed/31398786
http://dx.doi.org/10.3390/molecules24162873