Replacement of l-Amino Acids by d-Amino Acids in the Antimicrobial Peptide Ranalexin and Its Consequences for Antimicrobial Activity and Biodistribution

Infections caused by multidrug-resistant bacteria are a global emerging problem. New antibiotics that rely on innovative modes of action are urgently needed. Ranalexin is a potent antimicrobial peptide (AMP) produced in the skin of the American bullfrog Rana catesbeiana. Despite strong antimicrobial...

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Detalles Bibliográficos
Autores principales: Domhan, Cornelius, Uhl, Philipp, Kleist, Christian, Zimmermann, Stefan, Umstätter, Florian, Leotta, Karin, Mier, Walter, Wink, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720431/
https://www.ncbi.nlm.nih.gov/pubmed/31426494
http://dx.doi.org/10.3390/molecules24162987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720431/
https://www.ncbi.nlm.nih.gov/pubmed/31426494
http://dx.doi.org/10.3390/molecules24162987

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