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Replacement of l-Amino Acids by d-Amino Acids in the Antimicrobial Peptide Ranalexin and Its Consequences for Antimicrobial Activity and Biodistribution
Infections caused by multidrug-resistant bacteria are a global emerging problem. New antibiotics that rely on innovative modes of action are urgently needed. Ranalexin is a potent antimicrobial peptide (AMP) produced in the skin of the American bullfrog Rana catesbeiana. Despite strong antimicrobial...
Autores principales: | Domhan, Cornelius, Uhl, Philipp, Kleist, Christian, Zimmermann, Stefan, Umstätter, Florian, Leotta, Karin, Mier, Walter, Wink, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720431/ https://www.ncbi.nlm.nih.gov/pubmed/31426494 http://dx.doi.org/10.3390/molecules24162987 |
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