Regulation of Brain Cholesterol: What Role Do Liver X Receptors Play in Neurodegenerative Diseases?

Liver X Receptors (LXR) alpha and beta are two members of nuclear receptor superfamily documented as endogenous cholesterol sensors. Following conversion of cholesterol in oxysterol, both LXR isoforms detect intracellular concentrations and act as transcription factors to promote expression of targe...

Descripción completa

Detalles Bibliográficos
Autores principales: Mouzat, Kevin, Chudinova, Aleksandra, Polge, Anne, Kantar, Jovana, Camu, William, Raoul, Cédric, Lumbroso, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720493/
https://www.ncbi.nlm.nih.gov/pubmed/31398791
http://dx.doi.org/10.3390/ijms20163858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720493/
https://www.ncbi.nlm.nih.gov/pubmed/31398791
http://dx.doi.org/10.3390/ijms20163858

Ejemplares similares