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Determination of Reduced and Oxidized Coenzyme Q(10) in Canine Plasma and Heart Tissue by HPLC-ECD: Comparison with LC-MS/MS Quantification
Coenzyme Q(10) (Q(10)) plays an important role in mammals for energy production in the mitochondria, and as a potent antioxidant. Oxidation ratio (% oxidized in relation to total Q(10)) has been proposed as an important biomarker. A sensitive and reproducible HPLC-ECD method was developed for determ...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720496/ https://www.ncbi.nlm.nih.gov/pubmed/31366077 http://dx.doi.org/10.3390/antiox8080253 |