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Determination of Reduced and Oxidized Coenzyme Q(10) in Canine Plasma and Heart Tissue by HPLC-ECD: Comparison with LC-MS/MS Quantification

Coenzyme Q(10) (Q(10)) plays an important role in mammals for energy production in the mitochondria, and as a potent antioxidant. Oxidation ratio (% oxidized in relation to total Q(10)) has been proposed as an important biomarker. A sensitive and reproducible HPLC-ECD method was developed for determ...

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Detalles Bibliográficos
Autores principales: Schou-Pedersen, Anne Marie V., Schemeth, Dieter, Lykkesfeldt, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720496/
https://www.ncbi.nlm.nih.gov/pubmed/31366077
http://dx.doi.org/10.3390/antiox8080253