Combination of a Rapidly Penetrating Agonist and a Slowly Penetrating Antagonist Affords Agonist Action of Limited Duration at the Cellular Level

The capsaicin receptor TRPV1 (transient receptor potential vanilloid 1) has been an object of intense interest for pharmacological development on account of its critical role in nociception. In the course of structure activity analysis, it has become apparent that TRPV1 ligands may vary dramatically...

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Detalles Bibliográficos
Autores principales: Pearce, Larry V., Ann, Jihyae, Blumberg, Peter M., Lee, Jeewoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720535/
https://www.ncbi.nlm.nih.gov/pubmed/31302951
http://dx.doi.org/10.4062/biomolther.2019.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720535/
https://www.ncbi.nlm.nih.gov/pubmed/31302951
http://dx.doi.org/10.4062/biomolther.2019.013

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