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Synthesis of 1-azaspiro[4.4]nonan-1-oxyls via intramolecular 1,3-dipolar cycloaddition

Sterically shielded nitroxides of the pyrrolidine series have shown the highest resistance to reduction. Here we report the synthesis of new pyrrolidine nitroxides from 5,5-dialkyl-1-pyrroline N-oxides via the introduction of a pent-4-enyl group to the nitrone carbon followed by an intramolecular 1,...

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Detalles Bibliográficos
Autores principales: Khoroshunova, Yulia V, Morozov, Denis A, Taratayko, Andrey I, Gladkikh, Polina D, Glazachev, Yuri I, Kirilyuk, Igor A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720653/
https://www.ncbi.nlm.nih.gov/pubmed/31501671
http://dx.doi.org/10.3762/bjoc.15.200