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N-Acetyltransferase 1 Knockout Elevates Acetyl Coenzyme A Levels and Reduces Anchorage-Independent Growth in Human Breast Cancer Cell Lines

Elevated expression of N-acetyltransferase 1 (NAT1) is associated with invasive and lobular breast carcinomas as well as with bone metastasis following an epithelial-to-mesenchymal transition. We investigated the effect of NAT1 gene deletion in three different human breast cancer cell lines, MDA-MB-...

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Detalles Bibliográficos
Autores principales: Stepp, Marcus W., Salazar-González, Raúl A., Hong, Kyung U., Doll, Mark A., Hein, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720663/
https://www.ncbi.nlm.nih.gov/pubmed/31531019
http://dx.doi.org/10.1155/2019/3860426