Cargando…

Structural and Biological Characterizations of Novel High-Affinity Fluorescent Probes with Overlapped and Distinctive Binding Regions on CXCR4

CXC-type chemokine receptor 4 (CXCR4) is well known as a co-receptor for cellular entry and infection of human immunodeficiency virus type 1 (HIV-1). As an important member of the G protein-coupled receptor (GPCR) family, CXCR4 also mediates a variety of cellular processes and functions, such as cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Siyu, Meng, Qian, Schooley, Robert T., An, Jing, Xu, Yan, Huang, Ziwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720714/
https://www.ncbi.nlm.nih.gov/pubmed/31412600
http://dx.doi.org/10.3390/molecules24162928