Synthesis of New Quinoline-Piperonal Hybrids as Potential Drugs against Alzheimer’s Disease

Six quinoline-piperonal hybrids were synthesized and evaluated as potential drugs against Alzheimer’s disease (AD). Theoretical analysis of the pharmacokinetic and toxicological properties of the compounds suggest that they present good oral bio-availability and are also capable of penetrating the b...

Descripción completa

Detalles Bibliográficos
Autores principales: de Oliveira C. Brum, Juliana, Neto, Denise Cristian F., de Almeida, Joyce Sobreiro F. D., Lima, Josélia Alencar, Kuca, Kamil, França, Tanos Celmar C., Figueroa-Villar, José D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720848/
https://www.ncbi.nlm.nih.gov/pubmed/31416113
http://dx.doi.org/10.3390/ijms20163944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720848/
https://www.ncbi.nlm.nih.gov/pubmed/31416113
http://dx.doi.org/10.3390/ijms20163944

Ejemplares similares