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Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels

Ankyrin B (AnkB) is an adaptor and scaffold for motor proteins and various ion channels that is ubiquitously expressed, including in the brain. AnkB has been associated with neurological disorders such as epilepsy and autism spectrum disorder, but understanding of the underlying mechanisms is limite...

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Detalles Bibliográficos
Autores principales: Choi, Catherine S. W., Souza, Ivana A., Sanchez-Arias, Juan C., Zamponi, Gerald W., Arbour, Laura T., Swayne, Leigh Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720858/
https://www.ncbi.nlm.nih.gov/pubmed/31477143
http://dx.doi.org/10.1186/s13041-019-0494-8