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In Vitro Inhibitory Effects of APINACA on Human Major Cytochrome P450, UDP-Glucuronosyltransferase Enzymes, and Drug Transporters

APINACA (known as AKB48, N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide), an indazole carboxamide synthetic cannabinoid, has been used worldwide as a new psychoactive substance. Drug abusers take various drugs concomitantly, and therefore, it is necessary to characterize the potential of APINACA...

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Detalles Bibliográficos
Autores principales: Kim, Sunjoo, Choi, Won-Gu, Kwon, Mihwa, Lee, Sowon, Cho, Yong-Yeon, Lee, Joo Young, Kang, Han Chang, Song, Im-Sook, Lee, Hye Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720883/
https://www.ncbi.nlm.nih.gov/pubmed/31430908
http://dx.doi.org/10.3390/molecules24163000