Simultaneous Detection of the T790M and L858R Mutations in the EGFR Gene by Oligoribonucleotide Interference-PCR

A de novo single-nucleotide mutation in the EGFR gene can cause the development of lung cancer. EGFR tyrosine kinase inhibitors (EGFR-TKIs) are used for clinical treatment of such lung cancers, but acquired resistance often mitigates their efficacy. Accordingly, monitoring of de novo and acquired nu...

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Detalles Bibliográficos
Autores principales: Baba, Keisuke, Fujita, Toshitsugu, Tasaka, Sadatomo, Fujii, Hodaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720885/
https://www.ncbi.nlm.nih.gov/pubmed/31426517
http://dx.doi.org/10.3390/ijms20164020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720885/
https://www.ncbi.nlm.nih.gov/pubmed/31426517
http://dx.doi.org/10.3390/ijms20164020

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