Cargando…

Overcharging Effect in Electrospray Ionization Mass Spectra of Daunomycin-Tuftsin Bioconjugates

Peptide-based small molecule drug conjugates for targeted tumor therapy are currently in the focus of intensive research. Anthracyclines, like daunomycin, are commonly used anticancer drug molecules and are also often applied in peptide-drug conjugates. However, lability of the O-glycosidic bond dur...

Descripción completa

Detalles Bibliográficos
Autores principales: Pethő, Lilla, Mező, Gábor, Schlosser, Gitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720970/
https://www.ncbi.nlm.nih.gov/pubmed/31426442
http://dx.doi.org/10.3390/molecules24162981