Stem Cells from a Female Rat Model of Type 2 Diabetes/Obesity and Stress Urinary Incontinence Are Damaged by In Vitro Exposure to its Dyslipidemic Serum, Predicting Inadequate Repair Capacity In Vivo

Female stress urinary incontinence (FSUI) is prevalent in women with type 2 diabetes/obesity (T2D/O), and treatment is not optimal. Autograph stem cell therapy surprisingly has poor efficacy. In the male rat model of T2D/O, it was demonstrated that epigenetic changes, triggered by long-term exposure...

Descripción completa

Detalles Bibliográficos
Autores principales: Kovanecz, Istvan, Gelfand, Robert, Lin, Guiting, Sharifzad, Sheila, Ohanian, Alec, Ricks, Randy, Lue, Tom, Gonzalez-Cadavid, Nestor F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720976/
https://www.ncbi.nlm.nih.gov/pubmed/31430893
http://dx.doi.org/10.3390/ijms20164044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720976/
https://www.ncbi.nlm.nih.gov/pubmed/31430893
http://dx.doi.org/10.3390/ijms20164044

Ejemplares similares