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Stem Cells from a Female Rat Model of Type 2 Diabetes/Obesity and Stress Urinary Incontinence Are Damaged by In Vitro Exposure to its Dyslipidemic Serum, Predicting Inadequate Repair Capacity In Vivo
Female stress urinary incontinence (FSUI) is prevalent in women with type 2 diabetes/obesity (T2D/O), and treatment is not optimal. Autograph stem cell therapy surprisingly has poor efficacy. In the male rat model of T2D/O, it was demonstrated that epigenetic changes, triggered by long-term exposure...
Autores principales: | Kovanecz, Istvan, Gelfand, Robert, Lin, Guiting, Sharifzad, Sheila, Ohanian, Alec, Ricks, Randy, Lue, Tom, Gonzalez-Cadavid, Nestor F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720976/ https://www.ncbi.nlm.nih.gov/pubmed/31430893 http://dx.doi.org/10.3390/ijms20164044 |
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