Synthesis and Antiproliferative Activity of Novel A-Ring Cleaved Glycyrrhetinic Acid Derivatives

A series of new glycyrrhetinic acid derivatives was synthesized via the opening of its ring A along with the coupling of an amino acid. The antiproliferative activity of the derivatives was evaluated against a panel of nine human cancer cell lines. Compound 17 was the most active compound, with an I...

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Detalles Bibliográficos
Autores principales: Alho, Daniela P.S., Salvador, Jorge A.R., Cascante, Marta, Marin, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721064/
https://www.ncbi.nlm.nih.gov/pubmed/31416117
http://dx.doi.org/10.3390/molecules24162938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721064/
https://www.ncbi.nlm.nih.gov/pubmed/31416117
http://dx.doi.org/10.3390/molecules24162938

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