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Diselenides and Benzisoselenazolones as Antiproliferative Agents and Glutathione-S-Transferase Inhibitors

A series of variously functionalized selenium-containing compounds were purposely synthesized and evaluated against a panel of cancer cell lines. Most of the compounds showed an interesting cytotoxicity profile with compound 5 showing a potent activity on MCF7 cells. The ethyl amino derivative 5 act...

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Detalles Bibliográficos
Autores principales: Krasowska, Dorota, Iraci, Nunzio, Santi, Claudio, Drabowicz, Józef, Cieslak, Marcin, Kaźmierczak-Barańska, Julia, Palomba, Martina, Królewska-Golińska, Karolina, Magiera, Jakub, Sancineto, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721112/
https://www.ncbi.nlm.nih.gov/pubmed/31405214
http://dx.doi.org/10.3390/molecules24162914