Modulating Expression of Thioredoxin Interacting Protein (TXNIP) Prevents Secondary Damage and Preserves Visual Function in a Mouse Model of Ischemia/Reperfusion

Retinal neurodegeneration, an early characteristic of several blinding diseases, triggers glial activation, resulting in inflammation, secondary damage and visual impairment. Treatments that aim only at neuroprotection have failed clinically. Here, we examine the impact of modulating thioredoxin int...

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Detalles Bibliográficos
Autores principales: Coucha, Maha, Shanab, Ahmed Y., Sayed, Mohamed, Vazdarjanova, Almira, El-Remessy, Azza B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721134/
https://www.ncbi.nlm.nih.gov/pubmed/31443163
http://dx.doi.org/10.3390/ijms20163969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721134/
https://www.ncbi.nlm.nih.gov/pubmed/31443163
http://dx.doi.org/10.3390/ijms20163969

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