Insight into the PTP1B Inhibitory Activity of Arylbenzofurans: An In Vitro and In Silico Study

Protein tyrosine phosphatase 1B (PTP1B) plays a specific role as a negative regulator of insulin signaling pathways and is a validated therapeutic target for Type 2 diabetes. Previously, arylbenzofurans were reported to have inhibitory activity against PTP1B. However, detailed investigation regardin...

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Detalles Bibliográficos
Autores principales: Shrestha, Srijan, Seong, Su Hui, Park, Seul Gi, Min, Byung Sun, Jung, Hyun Ah, Choi, Jae Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721227/
https://www.ncbi.nlm.nih.gov/pubmed/31395821
http://dx.doi.org/10.3390/molecules24162893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721227/
https://www.ncbi.nlm.nih.gov/pubmed/31395821
http://dx.doi.org/10.3390/molecules24162893

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