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Insight into the PTP1B Inhibitory Activity of Arylbenzofurans: An In Vitro and In Silico Study
Protein tyrosine phosphatase 1B (PTP1B) plays a specific role as a negative regulator of insulin signaling pathways and is a validated therapeutic target for Type 2 diabetes. Previously, arylbenzofurans were reported to have inhibitory activity against PTP1B. However, detailed investigation regardin...
Autores principales: | Shrestha, Srijan, Seong, Su Hui, Park, Seul Gi, Min, Byung Sun, Jung, Hyun Ah, Choi, Jae Sue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721227/ https://www.ncbi.nlm.nih.gov/pubmed/31395821 http://dx.doi.org/10.3390/molecules24162893 |
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