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Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway

Targeting aberrant metabolism is a promising strategy for inhibiting cancer growth and metastasis. Research is now geared towards investigating the inhibition of glycolysis for anticancer drug development. Betulinic acid (BA) has demonstrated potent anticancer activities in multiple malignancies. Ho...

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Detalles Bibliográficos
Autores principales: Zheng, Yifeng, Liu, Pengxi, Wang, Neng, Wang, Shengqi, Yang, Bowen, Li, Min, Chen, Jianping, Situ, Honglin, Xie, Meiqi, Lin, Yi, Wang, Zhiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721262/
https://www.ncbi.nlm.nih.gov/pubmed/31531187
http://dx.doi.org/10.1155/2019/8781690