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Combination of Whole-Brain Radiotherapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors Improves Overall Survival in EGFR-Mutated Non-Small Cell Lung Cancer Patients with Brain Metastases

Brain metastases (BM) cause morbidity and mortality in patients with non-small cell lung cancer (NSCLC). The use of upfront epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) and withholding of whole-brain radiation therapy (WBRT) is controversial. We aim to investigate the im...

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Detalles Bibliográficos
Autores principales: Chen, Chien-Hung, Lee, Hsin-Hua, Chuang, Hung-Yi, Hung, Jen-Yu, Huang, Ming-Yii, Chong, Inn-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721307/
https://www.ncbi.nlm.nih.gov/pubmed/31370314
http://dx.doi.org/10.3390/cancers11081092