Early Colorectal Cancers Provide New Evidence for a Lynch Syndrome-to-CMMRD Phenotypic Continuum

Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome, caused by heterozygous mutations in the mismatch repair (MMR) genes. Biallelic mutations in these genes lead however, to constitutive mismatch repair deficiency (CMMRD). In this study, we follow the diagnostic journe...

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Detalles Bibliográficos
Autores principales: Fernández-Rozadilla, Ceres, Alvarez-Barona, Miriam, Schamschula, Esther, Bodo, Sahra, Lopez-Novo, Anael, Dacal, Andres, Calviño-Costas, Consuelo, Lancho, Angel, Amigo, Jorge, Bello, Xabier, Cameselle-Teijeiro, Jose Manuel, Carracedo, Angel, Colas, Chrystelle, Muleris, Martine, Wimmer, Katharina, Ruiz-Ponte, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721314/
https://www.ncbi.nlm.nih.gov/pubmed/31366136
http://dx.doi.org/10.3390/cancers11081081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721314/
https://www.ncbi.nlm.nih.gov/pubmed/31366136
http://dx.doi.org/10.3390/cancers11081081

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