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Diminished Condensin Gene Expression Drives Chromosome Instability That May Contribute to Colorectal Cancer Pathogenesis

Chromosome instability (CIN), or constantly evolving chromosome complements, is a form of genome instability implicated in the development and progression of many cancer types, however, the molecular determinants of CIN remain poorly understood. Condensin is a protein complex involved in chromosome...

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Detalles Bibliográficos
Autores principales: Baergen, Allison K., Jeusset, Lucile M., Lichtensztejn, Zelda, McManus, Kirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721357/
https://www.ncbi.nlm.nih.gov/pubmed/31357676
http://dx.doi.org/10.3390/cancers11081066