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Diminished Condensin Gene Expression Drives Chromosome Instability That May Contribute to Colorectal Cancer Pathogenesis
Chromosome instability (CIN), or constantly evolving chromosome complements, is a form of genome instability implicated in the development and progression of many cancer types, however, the molecular determinants of CIN remain poorly understood. Condensin is a protein complex involved in chromosome...
Autores principales: | Baergen, Allison K., Jeusset, Lucile M., Lichtensztejn, Zelda, McManus, Kirk J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721357/ https://www.ncbi.nlm.nih.gov/pubmed/31357676 http://dx.doi.org/10.3390/cancers11081066 |
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