The Transcriptional Roles of ALK Fusion Proteins in Tumorigenesis

Anaplastic lymphoma kinase (ALK) is a tyrosine kinase involved in neuronal and gut development. Initially discovered in T cell lymphoma, ALK is frequently affected in diverse cancers by oncogenic translocations. These translocations involve different fusion partners that facilitate multimerisation a...

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Detalles Bibliográficos
Autores principales: Ducray, Stephen P., Natarajan, Karthikraj, Garland, Gavin D., Turner, Suzanne D., Egger, Gerda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721376/
https://www.ncbi.nlm.nih.gov/pubmed/31366041
http://dx.doi.org/10.3390/cancers11081074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721376/
https://www.ncbi.nlm.nih.gov/pubmed/31366041
http://dx.doi.org/10.3390/cancers11081074

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