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The Transcriptional Roles of ALK Fusion Proteins in Tumorigenesis
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase involved in neuronal and gut development. Initially discovered in T cell lymphoma, ALK is frequently affected in diverse cancers by oncogenic translocations. These translocations involve different fusion partners that facilitate multimerisation a...
Autores principales: | Ducray, Stephen P., Natarajan, Karthikraj, Garland, Gavin D., Turner, Suzanne D., Egger, Gerda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721376/ https://www.ncbi.nlm.nih.gov/pubmed/31366041 http://dx.doi.org/10.3390/cancers11081074 |
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