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The Benefit of Reactivating p53 under MAPK Inhibition on the Efficacy of Radiotherapy in Melanoma

Radiotherapy (RT) in patients with melanoma historically showed suboptimal results, because the disease is often radioresistant due to various mechanisms such as scavenging free radicals by thiols, pigmentary machinery, or enhanced DNA repair. However, radiotherapy has been utilized as adjuvant ther...

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Detalles Bibliográficos
Autores principales: Krayem, Mohammad, Sabbah, Malak, Najem, Ahmad, Wouters, An, Lardon, Filip, Simon, Stephane, Sales, François, Journe, Fabrice, Awada, Ahmad, Ghanem, Ghanem E., Van Gestel, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721382/
https://www.ncbi.nlm.nih.gov/pubmed/31374895
http://dx.doi.org/10.3390/cancers11081093