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The Benefit of Reactivating p53 under MAPK Inhibition on the Efficacy of Radiotherapy in Melanoma
Radiotherapy (RT) in patients with melanoma historically showed suboptimal results, because the disease is often radioresistant due to various mechanisms such as scavenging free radicals by thiols, pigmentary machinery, or enhanced DNA repair. However, radiotherapy has been utilized as adjuvant ther...
Autores principales: | Krayem, Mohammad, Sabbah, Malak, Najem, Ahmad, Wouters, An, Lardon, Filip, Simon, Stephane, Sales, François, Journe, Fabrice, Awada, Ahmad, Ghanem, Ghanem E., Van Gestel, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721382/ https://www.ncbi.nlm.nih.gov/pubmed/31374895 http://dx.doi.org/10.3390/cancers11081093 |
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