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Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals

BACKGROUND: C-Type Lectin Domain Family 3 Member B (CLEC3B), is down-regulated in serum and tumor tissues in different cancers including hepatocellular carcinoma (HCC). However, the functions of CLEC3B in HCC remains elucidated. The aim of this study is to analyze the roles of CLEC3B in HCC. METHODS...

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Detalles Bibliográficos
Autores principales: Dai, Wenjuan, Wang, Yilin, Yang, Tianxiao, Wang, Jing, Wu, Weicheng, Gu, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721425/
https://www.ncbi.nlm.nih.gov/pubmed/31477130
http://dx.doi.org/10.1186/s12964-019-0423-6