Loss of BAP1 Is Associated with Upregulation of the NFkB Pathway and Increased HLA Class I Expression in Uveal Melanoma

One of the characteristics of prognostically infaust uveal melanoma (UM) is an inflammatory phenotype, which is characterized by high numbers of infiltrating T cells and macrophages, and a high HLA Class I expression. We wondered how this inflammation is regulated, and considered that one of the mos...

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Detalles Bibliográficos
Autores principales: Souri, Zahra, Wierenga, Annemijn P. A., van Weeghel, Christiaan, van der Velden, Pieter A., Kroes, Wilma G. M., Luyten, Gregorius P. M., van der Burg, Sjoerd H., Jochemsen, Aart G., Jager, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721427/
https://www.ncbi.nlm.nih.gov/pubmed/31382450
http://dx.doi.org/10.3390/cancers11081102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721427/
https://www.ncbi.nlm.nih.gov/pubmed/31382450
http://dx.doi.org/10.3390/cancers11081102

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